Alicia G. Arroyo graduated in Medicine from the Universidad Complutense of Madrid in 1989, beginning her scientific training as an undergraduate student at the Centro de Investigaciones Biológicas (CIB, CSIC). Later, she specialized in immunology at the Hospital de la Princesa (Madrid), where she wrote her doctoral thesis on new mechanisms of regulation of integrin cell adhesion receptors in human leukocytes (Universidad Autónoma of Madrid, 1994). In 1995 she moved to Dr. R.O. Hynes’ laboratory (MIT, Cambridge, USA), where she analyzed the in vivo function of alpha4 integrins in hematopoiesis and inflammation, in mice deficient or chimeric for these receptors. In 1999 she established her group at the Hospital Universitario de la Princesa (as CSIC Científico Titular) and after spending several years at the CNIC as Group Leader (2003-2017), she is currently Investigador Científico and Head of the Department of Molecular Biomedicine at the CIB. Her scientific interests focus on the characterization of the cellular principles and molecular pathways that contribute to blood flow actions during microvasculature remodeling and during intravascular surveillance by circulating monocytes. This research may lead to new strategies to improve tissue perfusion and repair after damage and to combat diseases related to particles present in the bloodstream such as tumor metastases or sepsis.